Detalhe da pesquisa
1.
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.
Cell;
181(6): 1329-1345.e24, 2020 06 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32445698
2.
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy.
Nature;
549(7671): 227-232, 2017 09 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28854171
3.
High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma.
Genome Res;
29(8): 1211-1222, 2019 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31249064
4.
C3D: a tool to predict 3D genomic interactions between cis-regulatory elements.
Bioinformatics;
35(5): 877-879, 2019 03 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30816925
5.
SMuRF: a novel tool to identify regulatory elements enriched for somatic point mutations.
BMC Bioinformatics;
19(1): 454, 2018 Nov 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30477433
6.
oxBS-450K: a method for analysing hydroxymethylation using 450K BeadChips.
Methods;
72: 9-15, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25175075
7.
Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer.
Mol Cancer Res;
20(1): 102-113, 2022 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34556523
8.
Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival.
Elife;
102021 01 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33427645
9.
Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.
Nat Cancer;
2(2): 157-173, 2021 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35122077
10.
PRMT5 inhibition disrupts splicing and stemness in glioblastoma.
Nat Commun;
12(1): 979, 2021 02 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33579912
11.
Epigenetic Switch-Induced Viral Mimicry Evasion in Chemotherapy-Resistant Breast Cancer.
Cancer Discov;
10(9): 1312-1329, 2020 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32546577
12.
Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors.
Cancer Cell;
36(6): 674-689.e6, 2019 12 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31735626
13.
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.
Cancer Cell;
35(5): 782-797.e8, 2019 05 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31085178
14.
A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.
Cancer Cell;
36(1): 51-67.e7, 2019 07 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31287992
15.
Convergence of BMI1 and CHD7 on ERK Signaling in Medulloblastoma.
Cell Rep;
21(10): 2772-2784, 2017 Dec 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29212025
16.
ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.
Cell Stem Cell;
21(2): 209-224.e7, 2017 08 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28712938
17.
Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.
Cancer Cell;
30(6): 891-908, 2016 Dec 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27960086
18.
Comparative methylome analysis identifies new tumour subtypes and biomarkers for transformation of nephrogenic rests into Wilms tumour.
Genome Med;
7(1): 11, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25763109
19.
Assessment of RainDrop BS-seq as a method for large-scale, targeted bisulfite sequencing.
Epigenetics;
9(5): 678-84, 2014 May.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24518816
20.
Using high-density DNA methylation arrays to profile copy number alterations.
Genome Biol;
15(2): R30, 2014 Feb 03.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24490765